Leukoplakia is the most common oral white lesion that is classified under potentially malignant disorder The lesion should start as homogeneous leukoplakia.

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Homogeneous leukoplakias: the most common type, are uniformly white plaques – common in the buccal (cheek) mucosa and usually of low malignant potential. Oral leukoplakia (leuko=white, plakia=patch) is a white patch in the mouth that There are two main types: homogenous and non-homogenous leukoplakia.

Leukoplakia may be potentially malignant (or in a small number may already be carcinomatous) and, thus, both behaviour (lifestyle) modification to eliminate risk factors, and active treatment of the lesion are indicated (Table 28.2):. Patient information is an important aspect in management. Removal of known risk factors (tobacco, alcohol, betel and trauma) is a mandatory step. Up to 45% of Leukoplakia is the most common potentially malignant disorder occuring in the oral cavity. It is of utmost significance to differentiate it from other benign Non-homogenous leukoplakia is a lesion of non-uniform appearance.

Homogeneous leukoplakia ppt

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The prevalence of leukoplakia among adults (15 years or older) has been reported as 3.6% in Sweden. Etiologic and clinical subgroups of leukoplakia showed the following prevalences: using the etiologic subgroups, idiopathic leukoplakia 0.7% and tobacco-associated leukoplakia 2.9%; using the clinical subgroups, homogeneous leukoplakia 3.5% and non-homogeneous leukoplakia 0.3%. Homogeneous leukoplakia: Here the plaque is generally uniform, thick and extends over a wider area. It presents with a corrugated and wrinkled surface texture. On being touched it appears leathery and dry with some superficial irregularities. Non-homogeneous leukoplakia: Here, the plaques are nodular with irregularities at certain places.

Leukoplakia is defined as a white patch or plaque that cannot be ascribed to any other clinical disease. Leukoplakia has long been known to be a precancerous lesion for oral squamous cell carcinoma. The rate of malignant transformation is not definitively known, but reports in the literature range widely from 0.13% to 17.5%.

Thick and white papillary lesions are formed which are collectively known as- verrucous leukoplakia. Homogeneous leukoplakia with central fissuring in the left buccal mucosa Non-homogeneous leukoplakia (ulcerative leukoplakia) right commissure: note the white lesion with ulceration Oral submucous fibrosis: note th e blanching in the lower labial mucosa Non-homogeneous leukoplakia (verrucous leukoplakia): note the raised, thick and white patches on Leukoplakia is a condition in which one or more white patches or spots (lesions) forms inside the mouth.

leukoplakia is broadly classified into homogeneous and non-homogeneous subtypes.[2, 3] The distinction between this two types is purely clinical, based on surface colour and morphological (thick-ness) characteristics, and do have some bearing on the out-come or prognosis. [6] Homogeneous plaques are predominantly white, of

Homogeneous leukoplakia ppt

Leukoplakia. Clinical types.

Leukoplakia lesions look like similar patches but are white as opposed to  5 Feb 2016 Laryngoscopy characteristics of vocal leukoplakia. Factors. Score. Definitions.
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Homogeneous leukoplakia ppt

Developmental white patches usually are present from birth or become apparent earlier in life, whilst leukoplakia generally affects middle aged or elderly people. Mayo Clinic does not endorse companies or products. Clinically, different forms of leukoplakias exist; homogeneous leukoplakia is characterized by a flat and uniform white plaque with well-defined margins (at least one). Non-homogeneous leukoplakia presents with areas of erythema accompanied by areas of nodular-ity and verrucousity (van der Waal, 2010).

Non-homogeous atau heterogenous leukoplakia, terdiri dari: a. Leukoplakia is the most common potentially malignant lesion of the oral cavity and can be categorised according to its clinical appearance as homogeneous or nonhomogenous. Tobacco and areca nut use, either alone or in combination are the most common risk factors for oral leukoplakia, but some oral leukoplakias are idiopathic. Some leukoplakias arise within fields of precancerized oral 13.
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Leukoplakia can result from diaphragm or cervical cap use; from developmental variants, such as benign acanthotic nonglycogenated epithelium; and, less often, from CIN or invasive carcinoma. 7 Leukoplakia is often a benign finding, but histologic sampling must be performed to distinguish between benign hyperkeratosis and neoplasia. 2,8 Growth of a significant lesion, such as keratinizing

erythroleukoplakia) and the higher grades of dysplasia. Homogeneous leukoplakia Non - Homogenous leukoplakia Speckled leukoplakia Nodular leukoplakia Verrucousleukoplakia Staging System [3] A clinical staging system for oral leukoplakia (OL system) on the lines of TNM staging was recommended by WHO in 2005 taking into account the size (L) and the histopathological features (P) of the lesion. Leukoplakia presents as white patches of the oral mucosa that cannot be wiped off with a gauze.


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A characteristic well-defined white patch of homogeneous leukoplakia on the left commissure in this bidi smoker. Although OL is mentioned in clinical reviews since 2it was first defined by World Health Himogeneous in 3 as a white patch or plaque which cannot otherwise be characterized clinically or pathologically as any other disease.